I actually published my debut novel INVADER with a print on demand publisher thinking it was the better choice, but now I'm hating every moment of it. You can imagine that the first book I ever saw an error on the cover description was mine.
I actually also wanted to use the subtitle COLONY MARS for the first book since it was a series, but later let my publisher know that I had changed my mind. But guess what I saw on the cover the day I received my copies of the book. Yes, there it was, glaring at me.
Apart from this, the book keeps going out of stock and it often takes my publisher about a month or more to get more supplies to the bookstores. But on the other hand, it's probably just the particular publisher of mine and not Print on Demand publishers in general.